August 1, 2025 - CORRESP: Correspondence

[LETTERHEAD OF REZOLUTE, INC.]

8-1-25

VIA EDGAR

Securities and Exchange Commission

Division of Corporation Finance

100 F. Street, N.E.

Washington, D.C. 20549

Re: Rezolute, Inc. (the "Company")

Registration Statement on Form S-3

File No. 333-288731

Ladies and Gentlemen:

In accordance with Rule 461 under the Securities Act of 1933, as amended, the undersigned respectfully requests that the effective date of the above-referenced Registration Statement be accelerated so that the same will become effective at 3:00 PM on August 8, 2025 or as soon thereafter as is practicable.

	Very truly yours,

	REZOLUTE, INC.

	By:	/s/Nevan Elam
	Name: Nevan Elam
	Title: Chief Executive Officer